California Highway Patrol spokesman Mario Lopez said, "at least eight have died from the Sunday night crash," he added, "38 injured people were taken to hospitals."
The Department of Transportation spokeswoman Michelle Profant said, "It's pretty ugly up there with body parts."
The bus was heading back to Mexico from Big Bear, afterwards the incident occurred around 6:35 p.m., according to report by CBS News site.
According to report by KCAL9's Andrea Fujii, there are 39 people inside the tour bus and four persons in the pickup truck.
Meanwhile, the cause of the crash accident was still under investigation but the preliminary observation believed the bus driver lost the bus control, flipped and fell on the pick-up truck.